Assessment of internal refractive index profile of stochastically inhomogeneous nuclear models via analysis of two-dimensional optical scattering patterns

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ARİFLER D., Guillaud M.

JOURNAL OF BIOMEDICAL OPTICS, vol.26, no.5, 2021 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 5
  • Publication Date: 2021
  • Doi Number: 10.1117/1.jbo.26.5.055001
  • Journal Name: JOURNAL OF BIOMEDICAL OPTICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Communication Abstracts, Compendex, EMBASE, INSPEC, MEDLINE, Metadex, Veterinary Science Database, Directory of Open Access Journals, Civil Engineering Abstracts
  • Keywords: cell analysis, diagnostics, finite-difference time-domain modeling, Gaussian random fields, Haralick features, light scattering, LIGHT-SCATTERING, AUTOMATIC CLASSIFICATION, LEUKEMIC-CELLS, RANDOM-FIELDS, MICROSCOPY, CANCER, SIMULATION, MORPHOLOGY, CYTOMETRY, DENSITY
  • Open Archive Collection: AVESIS Open Access Collection
  • Middle East Technical University Northern Cyprus Campus Affiliated: Yes

Abstract

Significance: Optical scattering signals obtained from tissue constituents contain a wealth of structural information. Conventional intensity features, however, are mostly dictated by the overall morphology and mean refractive index of these constituents, making it very difficult to exclusively sense internal refractive index fluctuations.