Ball lens coupled fiber-optic probe for depth-resolved spectroscopy of epithelial tissue

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Schwarz R., Arifler D., Chang S., Pavlova I., Hussain I., Mack V., ...Daha Fazla

OPTICS LETTERS, cilt.30, sa.10, ss.1159-1161, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 10
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1364/ol.30.001159
  • Dergi Adı: OPTICS LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1159-1161
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Orta Doğu Teknik Üniversitesi Kuzey Kıbrıs Kampüsü Adresli: Hayır

Özet

A ball lens coupled fiber-optic probe design is described for depth-resolved measurements of the fluorescence and reflectance properties of epithelial tissue. A reflectance target, fluorescence targets, and a two-layer tissue phantom consisting of fluorescent microspheres suspended in collagen are used to characterize the performance of the probe. Localization of the signal to within 300 μ m of the probe tip is observed by use of reflectance and fluorescence targets in air. Differential enhancement of the fluorescence signal from the top layer of the two-layer tissue phantom is observed. © 2005 Optical Society of America.